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updated 14.10.2019

Hepa AFP-IC Literature

23. Crescenzi M, Tessari A, Biasiolo A, Padoan A, Gallotta A, Fassina G, Panciatichi C, Rossetto O, Pontisso P, Basso D, Plebani M. Analytical Validation of a Biochip prototype for integrated analysis of AFP-IgM and SCCA-IgM serum biomarkers in patients with liver cirrhosis and hepatocellular carcinoma. Anal Methods. 7(2):629-637. 2015. doi: 10.1039/C4AY02495H
22. Gallotta A, Orzes E, Fassina G. Biomarkers Quantification with Antibody Arrays in Cancer Early Detection. Clin Lab Med. 32(1):33-45. 2012. doi: 10.1016/j.cll.2011.11.001
21. Biasiolo A, Tono N, Briarava M, Beneduce L, Fassina G, Farinati F, Giacomin A, Matteucci C, Sorrentino R, Nitti D, Gatta A , Pontisso P. Improved diagnostic accuracy for HCC using a combination of IgM-linked biomarkers. Dig Liver Dis. 43(S2):S91. 2011. doi: 10.1016/S1590-8658(11)60081-9
20. Gomiero C, Pengo P, Gallotta A, Biasiolo A, Tono N, Gatta A, Pontisso P, Matteucci C, Fassina G, Beneduce L. Improved detection of HCC by co-determination of IgM anti-AFP antibodies and AFP-IgM immune complexes. J Hepatol. 54:S382. 2011.
19. Jiang J, Wu C, Shen Y, Xu B, Zheng X, Li X, Xu N. Clinical Application of Determining Serum AFP-IgM Complexes for Diagnosis of Small Hepatocellular Carcinoma. Anticancer Res. 31:687-92. 2011.
18. Krygier R, Stefaniuk P, Mikula T, Dusza M, Jablonowska M, Cianciara J, Wasyluk H, Wiercinska-Drapalo A. Usefulness of alpha-fetoprotein as circulating Immune Complexes (AFP-IC) in the diagnosis of hepatocellular carcinoma in cirrhotic patients. Exp Clin Hep. 7:44-48. 2011.
17. Savitskaya Y, Rico G, Linares L, Gonzalez R, Tellez R, Estrada E, Marin N, Martinez E, Alfaro A, Ibarra C. Circulating Natural IgM Antibodies Against Angiogenin in the Peripheral Blood Sera of Patients with Osteosarcoma as Candidate Biomarkers and Reporters of Tumorigenesis. Biomark Cancer. 2:65-78. 2010. doi: 10.4137/BIC.S6040
16. Stefaniuk P, Janusz Cianciara J, Wiercinska-Drapalo A. Present and future possibilities for early diagnosis of hepatocellular carcinoma. World J Gastroenterol. 16:418-24. 2010.
15. Stefaniuk P, Krygier R, Dusza M, Jablonowska M, Mikula T, Dabrowska M, Cianciara J, Wiercinska-Drapalo A. Do we have more predictive HCC biomarkers? Usefulness of new generation of HCC biomarkers in immune complexes with immunoglobulins of the IgM class. Exp Clin Hep. 6:AB18-18. 2010.
14. Teofanescu I, Gologan E, Stefanescu G, Balan G. Surveillance of cirrhosis for hepatocellular carcinoma clinical validation of new serological biomarkers for improved hepatocellular carcinoma diagnosis. Rev Med Chir Soc Med Nat Iasi. 114:39-46. 2010.
13. Gallotta A, Pengo P, Beneduce L, Fassina G. Combinatorial approaches in cancer early detection. Drug Design and Discovery for Developing Countries (Eds. Megnassan E, Owono Owono L, Miertus S) ICS-UNIDO. 206-18. 2009.
12. Gallotta A, Zuin J, Veggiani G, Pengo P, Biasiolo A, Tono N, Gatta A, Pontisso P, Fassina G, Beneduce L. Combining SCCA-IgM and AFP-IgM levels increases accuracy of hepatocellular carcinoma detection. Dig Liver Dis. 41(5):A15. 2009. doi: 10.1016/j.dld.2009.02.038
11. Gallotta A, Zuin J, Veggiani G, Pengo P, Leon A, Gion M, Biasiolo A, Tono N, Gatta A, Pontisso P, Fassina G, Beneduce L. Combination of biomarkers-IgM by logistic regression improves diagnostic accuracy in hepatocellular carcinoma. Int J Biol Markers. 24:208. 2009.
10. Jingting J, Changping W, Ning X, Vibei Z, Jun W, Mei J, Bin X, Peter N, Xueguan Z. Clinical evaluation of serum alpha-fetoprotein-IgM immune complexes on the diagnosis of primary hepatocellular carcinoma. J Clin Lab Anal. 23(4):213-8. 2009. doi: 10.1002/jcla.20321
9. Kumar M, Sarin SK. Biomarkers of diseases in medicine. Current Trends in Science. 403-417. 2009.
8. Sheng SL, Wang Q, Huang G, Yu B, Qin WX. Simultaneous determination of alpha-fetoprotein immune complexes and alpha-fetoprotein concentration in hepatocellular carcinoma using dual-label time-resolved immunofluorometric assays. J Clin Lab Anal. 23(3):179-85. 2009. doi: 10.1002/jcla.20316
7. Beneduce L, Pesce G, Gallotta A, Zampieri F, Biasolo A, Tono N, Pontisso P, Fassina G. Hepatocellular carcinoma induces specific IgM-biomarkers immune complexes. Dig Liver Dis. 40(5):A32. 2008. doi: 10.1016/j.dld.2007.12.083
6. Giannelli G, Antonaci S. Hepatocellular carcinoma: tumoral or peritumoral disease?. Recenti Prog Med. 98(1):23-8. 2007.
5. Giannelli G, Fransvea E, Trerotoli P, Beaugrand M, Marinosci F, Lupo L, Nkontchou G, Dentico P, Antonaci S. Clinical validation of combined serological biomarkers for improved hepatocellular carcinoma diagnosis in 961 patients. Clin Chim Acta. 383(1-2):147-52. 2007. doi: 10.1016/j.cca.2007.05.014
4. Beneduce L, Gallotta A, Marino M, Fassina G. Improvement of sensitivity for liver cancer detection by simultaneous evaluation of SCCA-IgM, AFP-IgM complexes and free AFP. J Hepatol. 44:S97. 2006. doi: 10.1016/S0168-8278(06)80242-4
3. Giannelli G, Antonaci S. New frontiers in biomarkers for hepatocellular carcinoma. Dig Liver Dis. 38(11):854-9. 2006. doi: 10.1016/j.dld.2006.05.007
2. Beneduce L, Castaldi F, Marino M, Tono N, Gatta A, Pontisso P, Fassina G. Improvement of liver cancer detection with simultaneous assessment of circulating levels of free alpha-fetoprotein (AFP) and AFP-IgM complexes. Int J Biol Markers. 19:155-9. 2004.
1. Pontisso P, Fassina G, Quarta S, Ruvoletto M, Tono N, Castaldi F, Nigro A, Marino M, Beneduce L, Gatta A. Nanotecnologie nella diagnostica dell'epatocarcinoma. Atti del 14° Conv. Int. Attualità e Prospettive in Epatologia. 144-8. 2004.