A novel diagnostic procedure to avoid negative prostate biopsy
iXip index was created to verify the real need of prostate biopsy in a patient with suspected prostate cancer.
A blood sample and the prostate volume determined by ultrasound are sufficient to calculate iXip.
When iXip value is less than 0.2, prostate biopsy can be avoided.
Compared to indexes and methods currently available, iXip:
is more efficient and reliable;
is simple, safe and comfortable for the patient;
avoids unnecessary prostate biopsies.
Diagnostic Procedure
SUSPECT* Bone pain - Erectile dysfunction - Haematuria - Lower back pain - Pain during urination - Painful ejaculation - Urgent or frequent need to urinate - Weak urinary stream - Weight loss
NO
YES
First DIAGNOSIS** High levels of PSA Suspicious DRE Transrectal ultrasonography (TRUS)
NO
YES
Serum Level of PSA-IgM Prostate Volume by TRUS
< 0.2
> 0.2
(*) It is important that you contact your healthcare provider if you have any of these symptoms. (**) A. Heidenreich, et al. Guidelines on Prostate Cancer. European Association of Urology 2012.
